Article

Monitoring the Risk of Type-2 Circulating Vaccine-Derived Poliovirus Emergence during Roll-Out of Type-2 Novel Oral Polio Vaccine

2024-10-17

Abstract excerpt

<h4>Background/Objectives</h4> Although wild poliovirus type 2 has been eradicated, prolonged transmission of the live-attenuated virus contained in the type-2 oral polio vaccine (OPV2) in under-immunized populations has led to emergence of circulating vaccine derived poliovirus type-2 (cVDPV2). The novel OPV2 (nOPV2) was designed to be more genetically stable and reduce the chance of cVDPV2 emergence while retai...

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Literature Corpus work: 192a6b50-4e23-52bd-a8a4-2dc7a6316d54
DOI: 10.1101/2024.10.16.24315616

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