Article

Identification of inter- and intra-tumoral molecular phenotypes steering temozolomide resistance in patient-derived glioblastoma cells

2023-08-14

Abstract excerpt

<h4>Background</h4> Radiation therapy and chemotherapy using Temozolomide are the standard adjuvant treatments for patients with glioblastoma. Despite maximal treatment prognosis is still poor largely due to the emergence of Temozolomide resistance. This resistance is closely linked to the widely recognized inter- and intra-tumoral heterogeneity in glioblastoma, although the underlying mechanisms are not yet full...

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Literature Corpus work: 18a42284-b157-58dd-ac1b-204856d96a39
DOI: 10.1101/2023.08.11.552418

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