Article

Prolonged ovarian storage of mature <i>Drosophila</i> oocytes dramatically increases meiotic spindle instability

2019-06-19

Abstract excerpt

<h4>Summary</h4> More than 95% of fertilized Drosophila oocytes from outbred stocks develop fully regardless of maternal age, in contrast to human oocytes, which frequently generate non-viable aneuploid embryos. Since Drosophila oocytes are normally stored only briefly prior to ovulation, unlike their human counterparts, we investigated the effects of storage on oocyte quality. Using a novel system to acquire o...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: 1890c6d6-aa88-5e1a-8521-f9077f027fc6
DOI: 10.1101/675389

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

Prolonged ovarian storage of mature <i>Drosophila</i> oocytes dramatically increases meiotic spindle instabilityDOI 10.1101/675389Read

Prolonged ovarian storage of mature Drosophila oocytes dramatically increases meiotic spindle instabilitySemantic proximity Read

Fragile X mental retardation protein is a size-dependent translational activatorSemantic proximity Read

Acquisition of oocyte competence to develop as an embryo: integrated nuclear and cytoplasmic eventsSemantic proximity Read

Oogenesis: Ageing Oocyte Chromosomes Rely on Amazing Protein StabilitySemantic proximity Read

Dynamic mRNA degradome analyses indicate a role of histone H3K4 trimethylation in association with meiosis-coupled mRNA decay in oocyte agingSemantic proximity Read

Age‐related differences in the translational landscape of mammalian oocytesSemantic proximity Read

The prophase oocyte nucleus is a homeostatic G-actin bufferSemantic proximity Read

Effects of vitrification and cryostorage duration on single-cell RNA-Seq profiling of vitrified-thawed human metaphase II oocytesSemantic proximity Read

Meiotic spindle dynamics in human oocytes following slow-cooling cryopreservationSemantic proximity Read

Spatial single-cell sequencing of meiosis I arrested oocytes indicates acquisition of maternal transcripts from the somaSemantic proximity Read

Meiotic spindle imaging in human oocytes frozen with a slow freezing procedure involving high sucrose concentrationSemantic proximity Read

Sucrose concentration influences the rate of human oocytes with normal spindle and chromosome configurations after slow-cooling cryopreservation*Semantic proximity Read