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Meiotic spindle dynamics in human oocytes following slow-cooling cryopreservation

22 May 2009

Abstract excerpt

BACKGROUND: The demand for cryopreservation of human oocytes is increasing in assisted reproduction clinics and yet remains an experimental procedure. Surprisingly, little is known about the effects of cryopreservation on spindle-chromosome interactions and the recovery of meiotic spindle functionality. The goal of these studies was to evaluate the process of meiotic spindle reassembly and chromosome alignment in...

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PMID: 19465461
DOI: 10.1093/humrep/dep182

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