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Article

Mapping the functional interactions at the tumor-immune checkpoint interface

2021-10-07

Abstract excerpt

It is challenging to identify the tumor-immune system interactions that modulate immune states and immunotherapy responses due to the prohibitively complex space of possible interactions. Our statistical analysis framework, ImogiMap quantifies tumor-immune interactions based on their synergistic co-associations with immune-associated phenotypes. ImogiMap-based analyses recapitulated known interactions modulating i...

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Identifiers and source

Literature Corpus work
184ea194-a90e-5ab5-819c-3b7c472c874a
DOI
10.1101/2021.10.06.462889
Open publication

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Mapping the functional interactions at the tumor-immune checkpoint interfaceDOI 10.1101/2021.10.06.462889
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