TimiGP: Inferring cell-cell interactions and prognostic associations in the tumor immune microenvironment through gene pairs

Abstract excerpt

Determining the prognostic association of different immune cell types in the tumor microenvironment is critical for understanding cancer biology and developing new therapeutic strategies. However, this is challenging in certain cancer types, where the abundance of different immune subsets is highly correlated. In this study, we develop a computational method named TimiGP to overcome this challenge. Based on bulk...

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