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Enhanced Discrimination of<i>Clostridioides difficile</i>Transmission Using Whole Genome Sequencing and<i>In-Silico</i>Multi-locus Variable Number Tandem Repeat Analysis

2024-07-22

Abstract excerpt

<h4>ABSTRACT</h4> Whole genome sequencing (WGS) is used to establish genetic relatedness of bacteria and track outbreaks in healthcare settings. While WGS provides sufficient discriminatory power to make inferences about genetic relatedness and transmission for most bacterial species, WGS for Clostridioides difficile often fails to provide discriminatory power, even at low single nucleotide polymorphism (SNP) diff...

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Literature Corpus work
182a69af-5d7f-51d4-a0b7-75e35f1abead
DOI
10.1101/2024.07.22.24310821
Open publication

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Enhanced Discrimination of<i>Clostridioides difficile</i>Transmission Using Whole Genome Sequencing and<i>In-Silico</i>Multi-locus Variable Number Tandem Repeat AnalysisDOI 10.1101/2024.07.22.24310821
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