Article
A molecular epidemiological and transmission analysis of Clostridioides difficile using draft whole-genome sequencing in a single hospital.
BMC infectious diseases - 17 Sept 2024
Miyazaki Taito, Aoki Kotaro, Maeda Tadashi, Komori Kohji, Yoshizawa Sadako, Ishii Yoshikazu, Urita Yoshihisa, Tateda Kazuhiro
Abstract excerpt
BACKGROUND: The nosocomial transmission of toxin-producing Clostridioides difficile is a significant concern in infection control. C. difficile, which resides in human intestines, poses a risk of transmission, especially when patients are in close contact with medical staff. METHODS: To investigate the nosocomial transmission of C. difficile in a single center, we analyzed the genetic relationships of the...
Topics
- Humans
- Clostridioides difficile
- Clostridium Infections
- Whole Genome Sequencing
- Cross Infection
- Retrospective Studies
- Molecular Epidemiology
- Polymorphism, Single Nucleotide
- Female
- Male
- Genome, Bacterial
- Aged
- Middle Aged