Article

Spontaneous Cell Fusions as a Mechanism of Parasexual Recombination in Tumor Cell Populations

2020-03-10

Abstract excerpt

<h4>ABSTRACT</h4> Initiation and progression of cancers reflect the underlying process of somatic evolution, which follows a Darwinian logic, i.e ., diversification of heritable phenotypes provides a substrate for natural selection, resulting in the outgrowth of the most fit subpopulations. Although somatic evolution can tap into multiple sources of diversification, it is assumed to lack access to (para)sexual r...

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Literature Corpus work: 1825969d-99a5-5377-9a42-64d4e0bb19d4
DOI: 10.1101/2020.03.09.984419

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