Article

Perspectives on the History and Epidemiology of the Varicella Virus Vaccine and Future Challenges

2025-07-23

Abstract excerpt

The Varicella attenuated virus vaccine, developed in Japan in the 1970s, has dramatically reduced the number of pediatric chickenpox cases over the past 30 years due to its widespread use. However, a small number of cases of chickenpox, singles, and aseptic meningitis caused by vaccine strains have been reported. There are also issues that need to be addressed, such as breakthrough infections and the persistence o...

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Literature Corpus work: 180c9f6f-121d-525c-ba3e-2558ae6a19ab
DOI: 10.20944/preprints202507.1937.v1

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