Article

Epithelial-Mesenchymal Plasticity is Associated with Immunosuppressive Features in Canine Mammary Carcinomas

2025-09-21

Abstract excerpt

Epithelial-mesenchymal plasticity (EMP) is a cellular process activated in carcinoma cells to drive invasiveness, metastasis, and chemoresistance. Recently, we have demonstrated that activation of the EMP program also results in the assembly of an immunosuppressive tumor microenvironment and resistance to immunotherapy in an immunocompetent orthotopic murine model. However, it has yet to be shown whether these fin...

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Literature Corpus work: 18038546-b9d4-5552-98f5-26aa22a0c1e6
DOI: 10.1101/2025.09.19.677414

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