Article

A single-cell transcriptomic study reveals immune suppressive cancer cell-immune cell interactions in the triple negative canine breast cancers

2023-08-17

Abstract excerpt

Clinical trials show promising outcomes for dogs with advanced solid tumors following treatment with immune checkpoint inhibitors (ICIs). Triple-negative breast cancer (TNBC) is very aggressive with very low response rates to ICIs. No study defines how canine TNBC interacts with the immune system within the tumor microenvironment, which is investigated in this study at the single cell level. Single cell RNA sequen...

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Literature Corpus work: 5e506620-9047-5172-9f1a-1c02a958aa0f
DOI: 10.21203/rs.3.rs-3246929/v1

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