Article

Clonal Expansion of Bone Marrow CD8+ T Cells in Acute Myeloid Leukemia Patients at New Diagnosis and Post Chemotherapy

2020-08-02

Abstract excerpt

<h4>Background: </h4> CD8 + T cells are crucial adaptive immune effectors and express receptors (T cell receptors, TCRs) that specifically recognize and eradicate tumor cells. The diversity of the TCR repertoire is generated by specialized genetic diversification mechanisms, leading to an extremely variable TCR repertoire capable of recognizing a wide range of antigens. However, the variations in CD8 + TCR diversi...

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Literature Corpus work: 18033b71-1de2-5090-b970-575a15e248bb
DOI: 10.21203/rs.3.rs-50231/v1

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