Article

Inhibition of eukaryotic translation initiation factor 1A (eIF1A) and 3B (eIF3B) diminishes the psoriatic phenotype in two mouse models and human 3D model samples

2024-03-21

Abstract excerpt

<h4>Background</h4> Psoriasis is a systemic inflammatory disease for which new topical treatments are required. Psoriatic inflammation is associated with overexpression of eukaryotic translation initiation factors (eIFs), which critically regulate gene expression in many important cellular processes, including proliferation, apoptosis, and differentiation. However, the exact link between overexpression of eIF and...

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Literature Corpus work: 17e3a0a5-9684-5b51-bc76-9c86b5c8ab6d
DOI: 10.1101/2024.03.21.586074

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