Article

CP-25 inhibits keratinocyte proliferation and improves differentiation by increasing GRK2 colocalization with JAK1 in mouse model of psoriasis

2024-07-13

Abstract excerpt

<h4>Background: </h4> and Purpose: Psoriasis is chronic inflammatory skin disease mediated by interactions between Th17 cells and keratinocytes that lead to excessive proliferation and aberrant differentiation of keratinocytes. Given its anti-inflammatory and immune-regulatory effects on autoimmune arthritis and primary Sjögren’s syndrome, we investigated the effects of CP-25 on psoriasis and its underlying mechan...

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Literature Corpus work: ece78c8b-b011-527e-b888-61b3d112a409
DOI: 10.22541/au.172089579.93037086/v1

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