Article

Demixing of bacterial CipA and CipB proteins in mammalian cell cytosol provides an orthogonal self-assembly platform for producing isolable multi-phase intracellular crystals

2026-05-13

Abstract excerpt

Crystalline inclusion proteins CipA and CipB from Photorhabdus luminescens serve as versatile scaffolds for clustering genetically fused heterologous enzymes into crystalline inclusion bodies. Although engineered Cip crystals are known to function as solid biocatalysts for improving metabolite production in bacterial cells, the phase separation behavior of Cip proteins in non-bacterial cellular environments, as w...

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Literature Corpus work: 17d00d8d-a532-5854-9afb-bccaaf1b6a2c
DOI: 10.64898/2026.05.10.724141

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Demixing of bacterial CipA and CipB proteins in mammalian cell cytosol provides an orthogonal self-assembly platform for producing isolable multi-phase intracellular crystalsDOI 10.64898/2026.05.10.724141Read

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