Article
Cell cycle-dependent polar localization of an essential bacterial histidine kinase that controls DNA replication and cell division.
Cell - 2 Apr 1999
Jacobs C, Domian I J, Maddock J R, Shapiro L
Abstract excerpt
The master CtrA response regulator functions in Caulobacter to repress replication initiation in different phases of the cell cycle. Here, we identify an essential histidine kinase, CckA, that is responsible for CtrA activation by phosphorylation. Although CckA is present throughout the cell cycl...
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