Article

Quantifying Intratumor Heterogeneity by Key Genes Selected using Concrete Autoencoder

2021-09-06

Abstract excerpt

<h4>ABSTRACT</h4> The tumor cell population in cancer tissue has distinct molecular characteristics and exhibits different phenotypes, thus, resulting in different subpopulations. This phenomenon is known as Intratumor Heterogeneity (ITH), a major contributor to drug resistance, poor prognosis, etc. Therefore, quantifying the levels of ITH in cancer patients is essential, and many algorithms do so in different wa...

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Literature Corpus work: 1780339b-e461-580c-8151-999dff2890e7
DOI: 10.1101/2021.09.06.459161

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