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Modification of Mesenchymal Stem Cells by HMGB1 Promotes the Activity of Cav3.2 T-type Calcium Channel via PKA/β-catenin/γ-cystathionase Pathway

2021-10-18

Abstract excerpt

<title>Abstract</title> <p>Background: Mesenchymal stem cells (MSC) hold great promise for treating cardiovascular disease. Recently, we genetically modified MSCs with high mobility group box 1 (HMGB1), and these cells demonstrated high mobility by efficient migrating and homing to target neointima. The possible mechanism was investigated in the current study. <h4>Methods:</h4> Rat MSCs were transfected with lent...

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Literature Corpus work
171ac1f1-7192-5aee-8986-78931d8a7c78
DOI
10.21203/rs.3.rs-965121/v1
Open publication

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Modification of Mesenchymal Stem Cells by HMGB1 Promotes the Activity of Cav3.2 T-type Calcium Channel via PKA/β-catenin/γ-cystathionase PathwayDOI 10.21203/rs.3.rs-965121/v1
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