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Article

HMGB1-stimulated human primary cardiac fibroblasts exert a paracrine action on human and murine cardiac stem cells.

Journal of molecular and cellular cardiology - 1 Apr 2008

Rossini Alessandra, Zacheo Antonella, Mocini David, Totta Pierangela, Facchiano Antonio, Castoldi Raffaella, Sordini Paolo, Pompilio Giulio, Abeni Damiano, Capogrossi Maurizio C, Germani Antonia

Abstract excerpt

High Mobility Box 1 Protein (HMGB1) is a cytokine released into the extracellular space by necrotic cells and activated macrophages in response to injury. We recently demonstrated that HMGB1 administration into the mouse heart during acute myocardial infarction induces cardiac tissue regeneration...

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Source

Identifiers

PMID: 18328501
DOI: 10.1016/j.yjmcc.2008.01.009

Genes

HMGB1
TNF

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-18328501-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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