Article

The identification of a novel Ras nanocluster regulator

2020-01-01

Abstract excerpt

Ras proteins are crucial for the regulation of cellular proliferation, differentiation, and survival. These small GTPases act as a binary on/off switch, which reversibly binds to GTP or GDP, respectively. In humans, there are four Ras isoforms: KRAS4A, KRAS4B, HRAS and NRAS. They share almost complete sequence homology (~85%), however differ in the last 25 amino acids, termed the hypervariable region. This region...

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Literature Corpus work: 1709d7d3-a648-5d06-82f5-7df4c1f9ef8f
DOI: 10.17638/03114891

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