Elucidating Ras protein as a dual therapeutic target for inflammation and cancer: a review

Abstract excerpt

Cancer, one of the most dreadful diseases of the twenty-first century develops as a result of unregulated inflammatory responses and mutations of genes. In human cancers, among various mutated genes, the Ras gene is one of the most commonly mutated oncogenes. However, when it comes to inflammation, oncogenic Ras mutants can induce tumorigenesis without tumour suppression loss driven by inflammatory responses. Ras...

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