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Mesenchymal Stem Cell-Derived Exosomes and Intervertebral Disc Regeneration: Review

30 Jun 2022

Abstract excerpt

Intervertebral disc degeneration (IVDD) is a common cause of lower back pain (LBP), which burdens individuals and society as a whole. IVDD occurs as a result of aging, mechanical trauma, lifestyle factors, and certain genetic abnormalities, leads to loss of nucleus pulposus, alteration in the composition of the extracellular matrix, excessive oxidative stress, and inflammation in the intervertebral disc....

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PMID: 35806304
DOI: 10.3390/ijms23137306

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