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Integrative Transcriptomic Analysis and Interpretable Machine Learning Uncover a Core Biomarker Signature and Its Immu-noregulatory Network Mediating the Sodium Arsenite-MASLD Axis

2025-10-10

Abstract excerpt

<title>Abstract</title> <p>Sodium arsenite, a ubiquitous environmental hepatotoxin, has an ill-defined role in the pathophysiology of metabolic dysfunction-associated steatotic liver disease (MASLD). This study aimed to systematically identify key molecular targets linking sodium arsenite exposure to MASLD and to elucidate their potential mechanisms in regulating the liver immune microenvironment. Leveraging the...

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Literature Corpus work
16c19d22-e42d-5d4d-a05e-33c7a06339bf
DOI
10.21203/rs.3.rs-7692993/v1
Open publication

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Integrative Transcriptomic Analysis and Interpretable Machine Learning Uncover a Core Biomarker Signature and Its Immu-noregulatory Network Mediating the Sodium Arsenite-MASLD AxisDOI 10.21203/rs.3.rs-7692993/v1
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