Article

Distinct specific interactions of the UapA transporter with membrane lipids are critical for dimerization, ER-exit and function

2019-07-22

Abstract excerpt

Transporters are transmembrane proteins that mediate the selective translocation of solutes across biological membranes. Recently, we have shown that specific interactions with plasma membrane phospholipids are essential for formation and/or stability of functional dimers of the purine transporter, UapA, a prototypic eukaryotic member of the ubiquitous NAT family. Here, we show that distinct interactions of UapA w...

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Literature Corpus work: 16b1199e-3eb1-5901-bdd7-fdbf8d60df8b
DOI: 10.1101/710897

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