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Article

Modelling and mutational analysis of Aspergillus nidulans UreA, a member of the subfamily of urea/H⁺ transporters in fungi and plants.

Open biology - 1 Jun 2014

Sanguinetti Manuel, Amillis Sotiris, Pantano Sergio, Scazzocchio Claudio, Ramón Ana

Abstract excerpt

We present the first account of the structure-function relationships of a protein of the subfamily of urea/H(+) membrane transporters of fungi and plants, using Aspergillus nidulans UreA as a study model. Based on the crystal structures of the Vibrio parahaemolyticus sodium/galactose symporter (vSGLT) and of the Nucleobase-Cation-Symport-1 benzylhydantoin transporter from Microbacterium liquefaciens (Mhp1), we...

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PMID: 24966243
DOI: 10.1098/rsob.140070
PMCID: PMC4077062

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