Article

Comparing the folding landscapes of evolutionarily divergent procaspase-3

2022-01-12

Abstract excerpt

All caspases evolved from a common ancestor and subsequently developed into two general classes, inflammatory or apoptotic caspases. The caspase-hemoglobinase fold has been conserved throughout nearly one billion years of evolution and is utilized for both the monomeric and dimeric subfamilies of apoptotic caspases, called initiator and effector caspases, respectively. We compared the folding and assembly of proca...

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Literature Corpus work: 169fbe9e-e553-5c59-948a-172b370841a2
DOI: 10.1101/2022.01.12.476064

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