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Diversification of <i>Pseudomonas aeruginosa</i> biofilm populations under repeated phage exposures decreases the efficacy of the treatment

2024-07-30

Abstract excerpt

Phage therapy has been proposed as a therapeutic alternative to antibiotics for treatment of chronic, biofilm-related P. aeruginosa infections. To get a deeper insight into the complex biofilm-phage interactions, we investigated in the present study the effect of three successive exposures to lytic phages of biofilms formed by the reference strains PAO1 and PA14 as well as of two sequential clinical P. aeruginos...

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Literature Corpus work
169880fe-4500-5f53-b1f5-6c49ce65a634
DOI
10.1101/2024.07.30.602193
Open publication

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Diversification of <i>Pseudomonas aeruginosa</i> biofilm populations under repeated phage exposures decreases the efficacy of the treatmentDOI 10.1101/2024.07.30.602193
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