Article

Function of FMRP domains in regulating distinct roles of neuronal protein synthesis

2021-11-16

Abstract excerpt

The Fragile X Mental Retardation Protein (FMRP) is an RNA Binding Protein that regulates translation of mRNAs, essential for synaptic development and plasticity. FMRP interacts with a specific set of mRNAs and aids in their microtubule dependent transport and regulates their translation through its association with ribosomes. However, the biochemical role of individual domains of FMRP in forming neuronal granules...

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Literature Corpus work: 1669095d-cfcd-5654-b9cf-40db764f6b70
DOI: 10.1101/2021.11.15.468563

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