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Article

Dynamic association of the fragile X mental retardation protein as a messenger ribonucleoprotein between microtubules and polyribosomes.

Molecular biology of the cell - 1 Jan 2008

Wang Houping, Dictenberg Jason B, Ku Li, Li Wen, Bassell Gary J, Feng Yue

Abstract excerpt

The fragile X mental retardation protein (FMRP) is a selective RNA-binding protein that regulates translation and plays essential roles in synaptic function. FMRP is bound to specific mRNA ligands, actively transported into neuronal processes in a microtubule-dependent manner, and associated with...

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Identifiers

PMID: 17978095
DOI: 10.1091/mbc.e07-06-0583
PMCID: PMC2174202

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-17978095-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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Dynamic association of the fragile X mental retardation protein as a messenger ribonucleoprotein between microtubules and polyribosomes.PMID 17978095Read ↗

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FMRP promotes RNA localization to neuronal projections through interactions between its RGG domain and G-quadruplex RNA sequencesSemantic proximity Read ↗

m⁶A-dependent FMRP control of DGKκ translation underlies core Fragile X phenotypesSemantic proximity Read ↗

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