Article

Between- and within-host mutation of dengue virus

2025-10-14

Abstract excerpt

RNA viruses exhibit high mutation rates due to error-prone polymerases, leading to a diverse pool of viral haplotypes (also referred to as quasi-species) within infected hosts. While haplotypes have been well studied in chronic infections like HIV and HCV, diversity remains under-explored in acute infections like dengue (DENV), which are constrained by a short viremic phase. This study aimed to characterise the mu...

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Literature Corpus work: 1656225e-ca15-5db6-8292-e330d4cb84fd
DOI: 10.1101/2025.10.12.680595

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