Article

USP4-mediated CENPF deubiquitylation regulated tumor metastasis in colorectal cancer

2024-08-21

Abstract excerpt

<title>Abstract</title> <p>Metastasis is a major challenge for colorectal cancer (CRC) treatment. Here, we uncovered CENPF may be involved in CRC metastasis through bioinformatics mining and small interfering RNA (siRNA) targeted functional screening. We observed CENPF expression was preferentially increased in CRC tissues compared to adjacent normal tissues. More importantly, multicenter cohort study identified...

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Literature Corpus work: 164ca059-e0d8-5e6f-a75f-c57b220efb25
DOI: 10.21203/rs.3.rs-4681501/v1

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