Article

In silico screening of novel designed series of pyrazolidine compounds targeting Epidermal Growth Factor Receptor

2026-06-19

Abstract excerpt

<title>Abstract</title> <p>Cancer remains a leading cause of global mortality, with epidermal growth factor receptor (EGFR) playing a critical role in tumour progression and drug resistance. Despite the availability of several EGFR inhibitors, their clinical efficacy is often limited by toxicity and the emergence of resistant mutations. In the present study, a novel series of pyrazolidine derivatives was designed...

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Literature Corpus work: 1159794f-da12-5d3f-9afb-1171f7638498
DOI: 10.21203/rs.3.rs-9842360/v1

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