Article
Genomic rearrangements uncovered by genome-wide co-evolution analysis of a major nosocomial pathogen, Enterococcus faecium.
Microbial genomics - 1 Dec 2020
Top Janetta, Arredondo-Alonso Sergio, Schürch Anita C, Puranen Santeri, Pesonen Maiju, Pensar Johan, Willems Rob J L, Corander Jukka
Abstract excerpt
Enterococcus faecium is a gut commensal of the gastro-digestive tract, but also known as nosocomial pathogen among hospitalized patients. Population genetics based on whole-genome sequencing has revealed that E. faecium strains from hospitalized patients form a distinct clade, designated clade A1, and that plasmids are major contributors to the emergence of nosocomial E. faecium. Here we further explored the...
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