Article
Metabolic Analysis of Vitreous/Lens and Retina in Wild Type and Retinal Degeneration Mice.
International journal of molecular sciences - 26 Feb 2021
Murenu Elisa, Kostidis Sarantos, Lahiri Shibojyoti, Geserich Anna S, Imhof Axel, Giera Martin, Michalakis Stylianos
Abstract excerpt
Photoreceptors are the light-sensing cells of the retina and the major cell type affected in most inherited retinal degenerations. Different metabolic pathways sustain their high energetic demand in physiological conditions, particularly aerobic glycolysis. The principal metabolome of the mature retina has been studied, but only limited information is available on metabolic adaptations in response to key...
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