Article

Comprehensive mapping of mammalian transcriptomes identifies conserved genes associated with different cell differentiation states

2015-07-15

Abstract excerpt

Cell identity (or cell state) is established via gene expression programs, represented by “associated genes” with dynamic expression across cell identities. Here we integrate RNA-seq data from 40 tissues and cell types from human, chimpanzee, bonobo, and mouse to investigate the conservation and differentiation of cell states. We employ a statistical tool, “Transcriptome Overlap Measure” (TROM) to first identify c...

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Literature Corpus work: 15dd34bf-7c28-57fc-ab9e-68907335020f
DOI: 10.1101/022608

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