Article

Geometric inference of cross-species transcriptome correspondence using Gromov-Wasserstein optimal transport

2025-10-24

Abstract excerpt

Sequence homology reveals evolutionary gene correspondences, but identifying functionally corresponding genes within specific cell types or during cell fate specification remains non-trivial. Here, frameworks that translate insights from model organisms into other species would accelerate wet-lab studies, so we develop Species-OT, a cross-species transcriptome analysis framework using Gromov-Wasserstein optimal tr...

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Identifiers and source

Literature Corpus work: 78176189-f102-53b0-af92-33fb6bdb26f4
DOI: 10.1101/2025.10.23.684069

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