Article

Epigenetic reactivation of a neurodevelopmental phosphoprotein program in pituitary adenomas

2024-08-14

Abstract excerpt

<title>Abstract</title> <p><bold>Background:</bold> The protein kinase-phosphatase equilibrium is essential for eukaryotic development and homeostasis, but its epigenomic dysregulation in human tumors remains unexplored.<bold>Objectives/Methods:</bold> We employed an omics-based approach to elucidate the molecular mechanisms of pituitary adenomas, which comprise 20% of primary brain tumors. We created paired data...

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Literature Corpus work: 15d07079-3e65-5cd7-bb8c-d9b1580217df
DOI: 10.21203/rs.3.rs-4768687/v1

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