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Article

DNA methylation-based signatures classify sporadic pituitary tumors according to clinicopathological features

22 Feb 2021

Abstract excerpt

BACKGROUND: Distinct genome-wide methylation patterns cluster pituitary neuroendocrine tumors (PitNETs) into molecular groups associated with specific clinicopathological features. Here we aim to identify, characterize, and validate methylation signatures that objectively classify PitNET into clinicopathological groups. METHODS: Combining in-house and publicly available data, we conducted an analysis of the...

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PMID: 33631002
DOI: 10.1093/neuonc/noab044

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