Article
Phase <i>i</i> trials in melanoma: A framework to translate preclinical findings to the clinic
2015-03-03
Abstract excerpt
We present a, mathematical model driven, framework to implement virtual or imaginary clinical trials (phase i trials) that can be used to bridge the gap between preclinical studies and the clinic. The trial implementation process includes the development of an experimentally validated mathematical model, generation of a cohort of heterogeneous virtual patients, an assessment of stratification factors, and optimiz...
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Identifiers and source
- Literature Corpus work
- 677c1005-aa88-57ef-bfcf-a3de94540541
- DOI
- 10.1101/015925