Article

Interclonal cooperation and suppression shape early Ras-driven tumour growth

2026-02-20

Abstract excerpt

Cancer is generally thought to be caused by expansion of a single mutant cell. However, analyses of human early lesions show that tumours can originate from several genetically distinct cell populations 1–5 . How neighbouring mutant clones interact to shape tumourigenesis, and which driver genes mediate these effects is largely unexplored. Here, we use an in vivo mosaic Drosophila epithelial model to systematic...

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Literature Corpus work: 159f4750-fea6-5132-804a-6faf2065f85a
DOI: 10.64898/2026.02.19.706761

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