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Article

Optimizing clinico-genomic disease prediction across ancestries: a machine learning strategy with Pareto improvement.

Genome medicine - 4 Jun 2024

Gao Yan, Cui Yan

Abstract excerpt

BACKGROUND: Accurate prediction of an individual's predisposition to diseases is vital for preventive medicine and early intervention. Various statistical and machine learning models have been developed for disease prediction using clinico-genomic data. However, the accuracy of clinico-genomic prediction of diseases may vary significantly across ancestry groups due to their unequal representation in clinical...

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Identifiers

PMID: 38835075
DOI: 10.1186/s13073-024-01345-0
PMCID: PMC11149372

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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