Article

Region-specific molecular regulatory programs define epithelial identity, progenitor states, and mucus homeostasis in human distal airways

2026-06-19

Abstract excerpt

Small distal airways differ from proximal large airways in structure, airflow dynamics, and epithelial composition, and represent a central site of muco-obstructive lung disease pathogenesis. However, due in part to their inaccessibility, the molecular mechanisms that establish regional epithelial identity and govern mucociliary defense in distal airway epithelia remain poorly defined. Here, we integrate transcrip...

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Literature Corpus work: 158b853c-8afa-5362-9269-2476c4bc8f4e
DOI: 10.64898/2026.06.15.732400

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