Article

Fitness selection of hyperfusogenic measles virus F proteins associated with neuropathogenic phenotypes

2020-12-23

Abstract excerpt

Measles virus (MeV) is resurgent and caused >200,000 deaths in 2019. MeV infection can establish a chronic latent infection of the brain that can recrudesce months to years after recovery from the primary infection. Recrudescent MeV leads to fatal subacute sclerosing panencephalitis (SSPE) or measles inclusion body encephalitis (MIBE) as the virus spreads across multiple brain regions. Most clinical isolates of SS...

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Literature Corpus work: 1586a3b1-11fc-5892-bf59-658b365858ac
DOI: 10.1101/2020.12.22.423954

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