Article

SOX2 Maintains the Stemness of Retinoblastoma Stem-like Cells Through Hippo/YAP Signaling Pathway

2021-08-30

Abstract excerpt

<title>Abstract</title> <p><bold>Background:</bold> Cancer stem cells are responsible for tumor initiation and progression in various types of cancer, while, although the existence of retinoblastoma stem cells had been reported, the mechanisms supporting retinoblastoma stemness are poorly understood. In this study, a modified method for isolating retinoblastoma stem-like cells for mechanistic study was first esta...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: 1570adb2-be57-5099-88c1-35d814ee14dd
DOI: 10.21203/rs.3.rs-836788/v1

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

SOX2 Maintains the Stemness of Retinoblastoma Stem-like Cells Through Hippo/YAP Signaling PathwayDOI 10.21203/rs.3.rs-836788/v1Read

The retinoblastoma tumor suppressor and stem cell biology.Semantic proximity Read

Identification of tumorigenic retinal stem‐like cells in human solid retinoblastomasSemantic proximity Read

SKP1 promotes YAP-mediated colorectal cancer stemness via suppressing RASSF1Semantic proximity Read

Human embryonic stem cell-derived organoid retinoblastoma reveals a cancerous origin.Semantic proximity Read

Stemness and chemoresistance are imparted to the OC cells through TGFβ1 driven EMTSemantic proximity Read

Evaluation of Cancer Stem Cells in Patient-derived Xenografts of Retinoblastoma in a Chick Embryo-Chorioallontoic Membrane ModelSemantic proximity Read

Identification and characterization of human retinal stem cells capable of retinal regenerationSemantic proximity Read

SRY and OCT4 Are Required for the Acquisition of Cancer Stem Cell-Like Properties and Are Potential Differentiation Therapy TargetsSemantic proximity Read

Retinoblastoma from human stem cell-derived retinal organoidsSemantic proximity Read

<scp>SOX</scp>2 is required to maintain cancer stem cells in ovarian cancerSemantic proximity Read

SKP1 promotes YAP-mediated colorectal cancer stemness via suppressing RASSF1Semantic proximity Read

Sox2: regulation of expression and contribution to brain tumorsSemantic proximity Read