Article

Biophysical and structural studies of fibulin-2

2024-03-05

Abstract excerpt

Fibulin-2 is a multidomain, disulfide-rich, homodimeric protein which belongs to a broader extracellular matrix family. It plays an important role in the development of elastic fiber structures. Malfunction of fibulin due to mutation or poor expression can result in a variety of diseases including synpolydactyly, limb abnormalities, eye disorders leading to blindness, cardiovascular diseases and cancer. Traditiona...

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Literature Corpus work: 152bc58d-5769-55f2-815e-55ae3149b14c
DOI: 10.21203/rs.3.rs-3975382/v1

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