Back to search

Article

An RNAi screen reveals common host-virus gene signatures: implication for anti-viral drug discovery

2022-07-13

Abstract excerpt

Dengue is the most common mosquito-borne viral disease that in recent years has become a major international public health concern. Dengue is a tropical neglected disease with increasing global incidences, affecting millions of people worldwide, and without the availability of specific treatments to combat it. The identification of host-target genes essential for the virus life cycle, for which effective modulator...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work
14f111c8-d51f-5eba-8689-9f3b3ac76806
DOI
10.1101/2022.07.12.496853
Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest
Interactive article relationship graphSelect a related publication card to move it into the centre and load its closest explainable connections. Solid lines are source-backed structured connections. Dashed lines are semantic discovery signals and are not scientific evidence.
An RNAi screen reveals common host-virus gene signatures: implication for anti-viral drug discoveryDOI 10.1101/2022.07.12.496853
Integrative bulk and single‐cell transcriptome profiling analysis reveals IFI27 as a novel interferon‐stimulated gene in dengueSemantic proximity
High-throughput RNA interference screens integrative analysis: Towards a comprehensive understanding of the virus-host interplaySemantic proximity
Host gene targets for novel influenza therapies elucidated by high‐throughput RNA interference screensSemantic proximity
Small interference RNA profiling reveals the essential role of human membrane trafficking genes in mediating the infectious entry of dengue virusSemantic proximity
Response of the mosquito protein interaction network to dengue infectionSemantic proximity
Virus-host interactomics: new insights and opportunities for antiviral drug discoverySemantic proximity
Dengue Virus Infection of Aedes aegypti Requires a Putative Cysteine Rich Venom ProteinSemantic proximity
High content screening and computational prediction reveal viral genes that suppress innate immune responseSemantic proximity
Unraveling potential gene biomarkers for dengue infection through RNA sequencingSemantic proximity
High-Content Screening and Computational Prediction Reveal Viral Genes That Suppress the Innate Immune ResponseSemantic proximity
Host Gene Expression Profiling of Dengue Virus Infection in Cell Lines and PatientsSemantic proximity
RNAi: antiviral therapy against dengue virusSemantic proximity
Select a neighboring publication to make it the new centre.