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The <i>Legionella pneumophila</i> peptidoglycan recycling kinase, AmgK, is essential for survival and replication inside host alveolar macrophages

2025-03-21

Abstract excerpt

Bacterial cells are surrounded by a dynamic cell wall which in part is made up of a mesh-like peptidoglycan (PG) layer that provides the cell with structural integrity and resilience. In Gram-positive bacteria, this layer is thick and robust, whereas in Gram-negative bacteria, it is thinner and flexible as the cell is supported by an additional outer membrane. PG undergoes continuous turnover, with degradation pro...

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Identifiers and source

Literature Corpus work
14bdcd74-45b9-5198-b6aa-fefd2def548d
DOI
10.1101/2025.03.21.644609
Open publication

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