Article

Viral vector-driven trans-encapsidation of replicon RNAs as a rapid approach for the development of safe and economically attractive anti-enterovirus vaccines

2025-12-01

Abstract excerpt

Multiple enteroviruses are associated with life-threatening and economically important diseases, yet licensed vaccines are available only against poliovirus (worldwide) and enterovirus A71 (China). Both live attenuated and inactivated anti-poliovirus vaccines, while highly successful in preventing the disease, have important shortcomings. Live vaccine strains are inherently genetically unstable and can regain viru...

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Identifiers and source

Literature Corpus work: 1482cbce-eacb-526c-8573-2f40d95da2ee
DOI: 10.1101/2025.12.01.691592

Open publication

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