Development of enterovirus trans-encapsidation assays as tools to understand viral entry

Abstract excerpt

Enteroviruses (EVs) are globally important human and animal pathogens which cause a diverse spectrum of disease, ranging from febrile illness to paralysis. Despite decades of research, parts of the EV lifecycle remain poorly understood. Replicons, in which reporter genes replace the structural protein coding region, have proved useful for the study of EV biology. However, it is not possible to study the molecular...

Topics

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• Extracellular vesicles in disease
• Mosquito-borne diseases and control
• RNA and protein synthesis mechanisms
• RNA Research and Splicing
• Viral gastroenteritis research and epidemiology
• Viral Infections and Immunology Research
• Viral Infections and Outbreaks Research
• Virus-based gene therapy research

Identifiers and source

Literature Corpus work

0b39d0a4-4e23-5d35-bd67-0d877dfcc714

DOI

10.1101/2025.07.11.664324